Biography
Biography: Gunasekaran Ramanthan
Abstract
Neurodegenerative diseases have unbearable conditions particularly in aging population, Alzheimer’s disease (AD) is a cognitive decline, due to many Pathological and Neurophysiological changes occur mainly in basal forebrain neurons particularly, cholinergic neurons and some other complications. Yet no exact treatment for it. It’s a global health issue.
Neurotropic factors have crucial role in neural and non neural tissues. Mainly it’s initiating development and maintenance of brain tissue. Further, it has been reported that there is a sudden change in the neurotrophic factor secretion and its receptors in Alzheimer’s disease (AD) which may have a vital role in neuronal degeneration. For this reason, the neurotrophic factors study must be deeply and extensively investigate. Neurotrophic factors treatments known to promote faster regeneration of motor neurons (MN) and various central nervous system (CNS) neurons have been reported. However, the exact neurotrophic factor or factors not yet find out for clinical phase trials for Parkinson’s disease (PD) and AD. In this we discuss the underlying principle behind those neurotrophic factors and neurotrophic factor drugs for treatment of AD